Rune Rooms

Rune Rooms are special rooms that can change many elements of the run. Rune Rooms require two File:Keys.png keys to be opened, unlike most other special rooms. For a Rune Room to spawn, two things must happen;

• The floor Isaac is going to is the second floor of a chapter or the first floor of an alternate chapter (Downpour,  Dross,  Mines,  Ashpit,  Mausoleum,  Gehenna and Corpse)
• If Isaac has 2 or more keys, a Vault has a 1/3 chance to spawn and Rune Rooms has a 20% chance to replace it.

Effects

To activate the room's unique floor-wide effect, Isaac must step on the 4 pads located in the room. The effect depends on the type rune which appears on the pads. The runes and effects are:

• Hagalaz ‐ Destroys all rocks in each room.
• Jera ‐ Grants the Contract from Below effect.
• Ehwaz ‐ Spawns a trapdoor to the Great Gideon special crawlspace.
• Dagaz ‐ Prevents champion enemies from spawning.
• Ansuz ‐ Grants the Mercurius effect.
• Perthro ‐ Items switch between two possibilities.
• Berkano ‐ Killing enemies spawns blue flies and spiders.
• Algiz ‐ Grants a 7 sec shield in each room.
• Gebo ‐ Has a chance of spawning a slot in each room.
• Kenaz ‐ When entering an uncleared room, poisons all enemies.
• Fehu ‐ Grants midas tears that turn enemies golden.
• Othala ‐ Grants a temporary copy of a random item for each room.
• Ingwaz ‐ Most chests work like eternal chests.
• Sowilo ‐ Spawns a friendly version of the lowest hp enemy when clearing a room.

Layouts

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Notes

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Gallery

TBA

The Binding of Isaac: Compliance
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